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COPPER

DISCUSSION
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Copper Chemistry
A. Chemical characteristics
B. Physiological valences
C. Isotopes
II. Food Sources III. Safe and Adequate Dietary Dietary Intake
A. National Research Council
B. Usual Dietary Intake
C. Discrepancies
IV. Absorption
V. Transport and Delivery to Tissues
VI. Elimination
VII. Biochemical and Physiological Function
A. Energy Metabolism
1. Cytochrome C. Oxidase
B. Antioxidant Functions
1. Cu-Zn Superoxide Dismutase (SOD)
2. Metallothioneins
3. Ceruloplasmin
C. Other Copper Containing Proteins
1. Sysyl Oxidase
2. Tyrosinase
3. Factor V and VII
4. Cartilage Matrix Glycoprotein
5. Dopamine-beta-monooxygenase
VIII. Genetic Disorders of Copper Metabolism
A. Wilson disease
B. Menkes' syndrome
IX. Acquired Copper Deficiency
X. Copper: An antioxidant Nutrient?
XI. Prospects for a Recommended Dietary Allowance

LINKS
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http://www.chiff.com/vitamins/copper.htm
Chiff.com has information on the role of copper and its impact on health. Also includes information on sources.

http://healthyeatingclub.com/info/books-phds/books/foodfacts/html/data/data5i.html
Elements: 33: Copper has information on food intake, use and food charts.

http://emedicine.medscape.com/article/183456-overview
emedicine has information on Wilson's disease including overview, differential diagnoses, treatment and other information.

http://www.healthvitaminsguide.com/minerals/copper.htm
HealthVitaminsGuide.com has information on copper, including roles and sources.

http://www.hoptechno.com/book29m.htm
Hopkins Technology has Hopkins Technology. This site has information on copper and its role in health. Also contains content.

http://www.indiadiets.com/foods/food_nutrients/Minerals/Copper.htm
Indiadiet Foods has health information and the sources of copper.

http://www.mayoclinic.com/health/wilsons-disease/DS00411
Mayo Clinic has a description and information on Wilson's disease.

http://digestive.niddk.nih.gov/ddiseases/pubs/wilson/
National Digestive diseases Information Clearinghouse has information on Wilson disease which is high copper content.

http://www.whfoods.com/genpage.php?tname=nutrient&dbid=53
The World's healthiest foods has a page regarding the benefits of copper and foods it is found in.

http://www.wilsonsdisease.org/
Wilson Disease Association has information regarding this disease.

REFERENCES/RESOURCES
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Danks, D.M. 1988. Copper deficiency in humans. Ann. Rev. Nutrition 8: 235-257. Harris, E.D. 1997. Copper. IN: Handbook of Nutritionally Essential Mineral Elements. (O'Dell, B.L. and R.A. Sunde., eds.), pp. 231-273. Marcel Dekker, Inc., New York, NY

Johnson, M.A., J.G. Fischer, and S.E. Kays. 1992. Is copper an antioxidant nutrient? Crit. Rev. Food Sci. Nutr. 32: 1-31.

Kevay, L.M., S.D. inHyg., S.J. Reck, R.A. Jacob, G.M. Logan, J.M> Munoz, and H.H. Sandstead. 1980. The requirement for copper: healthy men fed conventional, American Diets. American Journal Clinical Nutrition 33: 45-50.

Linder, M.C. and M. Hazegh-Azam. 1996. Copper biochemistry and molecular biology. American Journal Clinical Nutrition 63: 797S-811S.

Milne, D.B. and F.H. Nielsen. 1996. Effects of a diet low in copper on copper-status indicators in postmenopausal women. American Journal Clinical Nutrition 63: 358-364.

Olivares, M. and R. Uay. 1996. Copper as an essential nutrient. America Journal Clinical Nutrition 63: 791S- 796S.

Schein berg, I.H. and I. Sternleib. 1996. Wilson disease an idiopathic copper toxicosis. American Journal Clinical Nutrition 63: 842S-845S.

Turnland, J.R., W.R. Keyes, H.L. Anderson, and L.L. Acord. 1989. American Journal Clinical Nutrition 49: 870-878.

Wildman, R.E., D.M. Medeiros, R.L. Hamlin, H. Stills, A. Jones, and J.D. Bonagura. 1996. Aspects of cardiomyopathy in copper deficient pigs. Biol. Trace Elem. Res. 55: 55-70.



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